FlexStream has spray nozzles mounted in the aspect partitions on the processor. While That is an ideal nozzle situation (from a processing point of view), it nonetheless carries the risk of uncontrolled above wetting. Hence, Together with the FlexStream, particles are pneumatically driven clear of the region of high humidity just before the nozzle strategies by a protective air stream taken within the usual course of action air.
Flexibility: Fluidized bed processors can be employed for a variety of pharmaceutical processing programs, such as drying, granulation, and coating of particles, along with for powder mixing and particle dimensions reduction.
By comprehension the principles and programs of your FBD method, pharmaceutical producers can enrich their drying and granulation procedures, leading to substantial-high quality products and solutions and improved efficiency.
FBP requires obtaining the powder in a very fluidized state immediately after currently being pressurized with warm air and acquiring handed below the solution bowl. Warm air constantly holds the particles in an air medium to receive dry, this is also referred to as a fluidized state.
The fluidized bed dryer is really a dynamic drying procedure with apps in quite a few industries. This versatile Resolution takes advantage of the principles of fluidization to supply rapid, successful, and evenly distributed drying.
Optical methods including UV/vis or NIR spectroscopy can be extremely strong equipment to analyze An array of product or service properties. In procedures involving moist and sticky powders, nevertheless, it's important to ensure that the process has a transparent look at of the products.
5.15 Clear away the products container immediately after shaking & rack the material. Once more reset the solution container & operate for more drying. Get out the granules intermittently within the sampling point as and when expected for checking the Loss on Drying (LOD).
Procedure ControlGEA has built-in website its knowledge and practical experience in pharmaceutical fluid mattress processors to aid operators observe and Handle the procedure in a straightforward and self explanatory way.
Inlet air temperature and humidity: The temperature and humidity of your inlet air can impact the effectiveness of your fluidized bed dryer.
Once the gas or air velocity is greater, it reaches some extent in which the drag power exerted within the particles overcomes their bodyweight, creating them to be suspended from the fluidized bed.
In general, an SFM exam could be a useful Instrument for optimizing the overall performance of the fluid bed dryer and enhancing the standard more info of the dried item.
Dryer: warm air is blown through a perforated distributor to fast and gently dry supplies until the expected residual humidity information is attained. Humidity evaporated through the solution is fatigued Together with the drying air, supplying pretty limited processing times.
The dryer is built up of stainless-steel or plastic. A detachable bowl is positioned at the bottom of your dryer, and that is utilized for charging & discharging.
The specified or targeted stop of drying course of action is attained by testing decline on drying (LOD) at the end of drying approach.